PLAUR 抗体 (AA 128-167)
Quick Overview for PLAUR 抗体 (AA 128-167) (ABIN7599902)
抗原
See all PLAUR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 128-167
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原理
- Anti-uPA Receptor/U-PAR/PLAUR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-uPA Receptor/U-PAR/PLAUR Antibody Picoband® (ABIN7599902). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human uPA Receptor/U-PAR/PLAUR recombinant protein (Position: E128-R167).
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亚型
- IgG
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anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 13-114) antibody
PLAUR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 201-300) antibodyPLAUR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 23-305) antibodyPLAUR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1D1B11 unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 23-305) antibodyPLAUR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) antibodyKO Validated PLAUR 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 221-305) antibodyPLAUR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 25-134) antibodyPLAUR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 1-335) antibodyPLAUR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) antibody (PE)PLAUR 适用: 人 FACS 宿主: 小鼠 Monoclonal VIM5 PE
anti-Plasminogen Activator, Urokinase Receptor (PLAUR) (AA 136-166) antibodyPLAUR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4065-4066 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Borglum, A., Anette, B., Roldan, A. L., Blasi, F., Bolund, L., Kruse, T. A. Assignment of the gene for urokinase-type plasminogen activator receptor to chromosome 19q13. 2. Borglum, A. D., Byskov, A., Ragno, P., Roldan, A. L., Tripputi, P., Cassani, G., Dano, K., Blasi, F., Bolund, L., Kruse, T. A. Assignment of the urokinase-type plasminogen activator receptor gene (PLAUR) to chromosome 19q13.1-q13.2. Am. J. Hum. Genet. 50: 492-497, 1992. 3. Llinas P, Le Du MH, Gårdsvoll H, et al. (May 2005). "Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide". -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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别名
- PLAUR
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背景
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Synonyms: Urokinase plasminogen activator surface receptor, U-PAR, Monocyte activation antigen Mo3, uPAR, CD87, Plaur, MO3, UPAR
Tissue Specificity: Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Background: PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.
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分子量
- 45 kDa
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基因ID
- 5329
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UniProt
- Q03405
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途径
- Inositol Metabolic Process
抗原
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