LARP1 抗体 (AA 123-401)
Quick Overview for LARP1 抗体 (AA 123-401) (ABIN7599861)
抗原
See all LARP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-401
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原理
- Anti-LARP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-LARP1 Antibody Picoband® (ABIN7599861). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LARP1 recombinant protein (Position: K123-E401).
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亚型
- IgG
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anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) antibody
LARP1 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 1-1019) antibodyLARP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 36-85) antibodyLARP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (AA 107-156) antibodyLARP1 适用: 人, 兔, Cow, 犬, 豚鼠, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (N-Term) antibodyLARP1 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-La Ribonucleoprotein Domain Family, Member 1 (LARP1) (N-Term) antibodyLARP1 适用: 人, 小鼠, 兔, 大鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chauvet, S., Maurel-Zaffran, C., Miassod, R., Jullien, N., Pradel, J., Aragnol, D. dlarp, a new candidate Hox target in Drosophila whose orthologue in mouse is expressed at sites of epithelium/mesenchymal interactions. Dev. Dyn. 218: 401-413, 2000. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/16/2008. 3. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 5: 277-286, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))
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别名
- LARP1
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背景
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Synonyms: Interferon regulatory factor 9,IRF-9,IFN-alpha-responsive transcription factor subunit,ISGF3 p48 subunit,Interferon-stimulated gene factor 3 gamma,ISGF-3 gamma,Transcriptional regulator ISGF3 subunit gamma,IRF9,ISGF3G,
Tissue Specificity: Leukocytes.
Background: La-related protein 1 (LARP1) is a 150 kDa protein that in humans is encoded by the LARP1 gene. La-related protein 1 (LARP1) is a ubiquitously expressed RNA binding protein that promotes both global and specific mRNA translation in cells. LARP1 belongs to the La-related protein family and contains two RNA binding domains, a La motif (LAM), and a neighboring RNA recognition motif-like (RRM-L) domain. Research studies indicate that LARP1 acts downstream of mTORC1 to facilitate cell proliferation and growth by promoting global mRNA translation and translation of mRNAs containing a 5'Terminal Oligo-Pyrimidine (5'TOP) motif, which code for translational machinery components. At the molecular level, LARP1 associates with 5'TOP mRNAs and multiple translation machinery components to positively regulate translation. Additional studies show that LARP1 expression is upregulated in hepatocellular carcinoma (HCC) patients and that high LARP1 expression in HCC negatively correlates with survival rate.
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分子量
- 150 kDa
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基因ID
- 23367
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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