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MMP19 抗体 (AA 120-437)

This anti-MMP19 antibody is a 兔 多克隆 antibody detecting MMP19 in WB, IHC, ELISA, ICC, FACS 和 IF. Suitable for 人.
产品编号 ABIN7599830
发货至: 中国

Quick Overview for MMP19 抗体 (AA 120-437) (ABIN7599830)

抗原

See all MMP19 抗体
MMP19 (Matrix Metallopeptidase 19 (MMP19))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP19 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)
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    AA 120-437

    原理

    Anti-MMP19 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MMP19 Antibody Picoband® (ABIN7599830). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MMP19 recombinant protein (Position: L120-D437).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Cossins, J., Dudgeon, T. J., Catlin, G., Gearing, A J. H., Clements, J. M. Identification of MMP-18, a putative novel human matrix metalloproteinase. Biochem. Biophys. Res. Commun. 228: 494-498, 1996. 2. Hazlewood, R. J., Roos, B. R., Solivan-Timpe, F., Honkanen, R. A., Jampol, L. M., Gieser, S. C., Meyer, K. J., Mullins, R. F., Kuehn, M. H., Scheetz, T. E., Kwon, Y. H., Alward, W. L. M., Stone, E. M., Fingert, J. H. Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly. Hum. Mutat. 36: 369-378, 2015. 3. Moore, M., Salles, D., Jampol, L. M. Progressive optic nerve cupping and neural rim decrease in a patient with bilateral autosomal dominant optic nerve colobomas. Am. J. Ophthal. 129: 517-520, 2000.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    MMP19 (Matrix Metallopeptidase 19 (MMP19))

    别名

    MMP19

    背景

    Synonyms: Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25,

    Tissue Specificity: Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen .

    Background: Matrix metalloproteinase-19 (MMP-19) also known as matrix metalloproteinase RASI is an enzyme that in humans is encoded by the MMP19 gene. This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene.

    分子量

    54 kDa

    基因ID

    4327

    UniProt

    Q99542
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