SECISBP2 抗体 (AA 12-854)
Quick Overview for SECISBP2 抗体 (AA 12-854) (ABIN7599828)
抗原
See all SECISBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-854
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原理
- Anti-SECISBP2 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-SECISBP2 Antibody Picoband® (ABIN7599828). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.
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亚型
- IgG
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anti-SECIS Binding Protein 2 (SECISBP2) (AA 585-854) antibody
SECISBP2 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) (Internal Region) antibodyVerified SECISBP2 适用: 人, 小鼠 WB, ELISA, IF, IHC, IP, ICC 宿主: 山羊 Polyclonal unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) antibodySECISBP2 适用: 人, 小鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) (AA 106-205) antibodySECISBP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) (AA 1-854) antibodySECISBP2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) (Internal Region) antibodySECISBP2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) (AA 159-208) antibodySECISBP2 适用: 人, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) antibodySECISBP2 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2957C2a unconjugated
anti-SECIS Binding Protein 2 (SECISBP2) antibodySECISBP2 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Catli, G., Fujisawa, H., Kirbiyik, O., Mimoto, M. S., Gencpinar, P., Ozdemir, T. R., Dundar, B. N., Dumitrescu, A. M. A novel homozygous selenocysteine insertion sequence binding protein 2 (SECISBP2, SBP2) gene mutation in a Turkish boy. Thyroid 28: 1221-1223, 2018. 2. Copeland, P. R., Fletcher, J. E., Carlson, B. A., Hatfield, D. L., Driscoll, D. M. A novel RNA binding protein, SBP2, is required for the translation of mammalian selenoprotein mRNAs. EMBO J. 19: 306-314, 2000. 3. Dumitrescu, A. M., Liao, X.-H., Abdullah, M. S. Y., Lado-Abeal, J., Majed, F. A., Moeller, L. C., Boran, G., Schomburg, L., Weiss, R. E., Refetoff, S. Mutations in SECISBP2 result in abnormal thyroid hormone metabolism. Nature Genet. 37: 1247-1252, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SECISBP2 (SECIS Binding Protein 2 (SECISBP2))
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别名
- SECISBP2
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 105 kDa
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基因ID
- 79048
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UniProt
- Q96T21
抗原
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