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FDPS 抗体 (AA 12-347)

This anti-FDPS antibody is a 兔 多克隆 antibody detecting FDPS in WB 和 ELISA. Suitable for 大鼠 和 小鼠.
产品编号 ABIN7599816
发货至: 中国

Quick Overview for FDPS 抗体 (AA 12-347) (ABIN7599816)

抗原

See all FDPS 抗体
FDPS (Farnesyl Diphosphate Synthase (FDPS))

适用

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大鼠, 小鼠

宿主

  • 49
  • 10

克隆类型

  • 47
  • 12
多克隆

标记

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This FDPS antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 11
    • 7
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    AA 12-347

    原理

    Anti-FDPS/FPS Picoband® Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-FDPS/FPS Picoband® Antibody (ABIN7599816). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse FDPS/FPS recombinant protein (Position: Q12-K347).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Heinzmann, C., Clarke, C. F., Klisak, I., Mohandas, T., Sparkes, R. S., Edwards, P. A., Lusis, A. J. Dispersed family of human genes with sequence similarity to farnesyl pyrophosphate synthetase. Genomics 5: 493-500, 1989. 2. Krisans, S. K., Ericsson, J., Edwards, P. A., Keller, G. A. Farnesyl-diphosphate synthase is localized in peroxisomes. J. Biol. Chem. 269: 14165-14169, 1994. 3. Scott, A. F. Personal Communication. Baltimore, Md. 11/9/2006.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    FDPS (Farnesyl Diphosphate Synthase (FDPS))

    别名

    Fdps

    背景

    Synonyms: Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Cholesterol-regulated 39 kDa protein, CR 39, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase, Fdps

    Tissue Specificity: Expressed ubiquitously.

    Background: Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that in humans is encoded by the FDPS gene. It is mapped to 3 F1, 3 39.01 cM. This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    40 kDa

    基因ID

    110196

    UniProt

    Q920E5

    途径

    Regulation of Muscle Cell Differentiation
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