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ISL1 抗体 (AA 118-289)

This anti-ISL1 antibody is a 兔 多克隆 antibody detecting ISL1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7599791
发货至: 中国

Quick Overview for ISL1 抗体 (AA 118-289) (ABIN7599791)

抗原

See all ISL1 抗体
ISL1 (ISL LIM Homeobox 1 (ISL1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ISL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 118-289

    原理

    Anti-Islet 1/ISL1 Antibody Picoband®

    产品特性

    Anti-Islet 1/ISL1 Antibody Picoband® (ABIN7599791). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ISL1 recombinant protein (Position: D118-Q289). Human Islet 1/ISL1 shares 100% amino acid (aa) sequence identity with both mouse and rat ISL1.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: ISL1 ISL1 transcription factor, LIM/homeodomain, (islet-1)". 2. Gay F, Anglade I, Gong Z, Salbert G (October 2000). "The LIM/homeodomain protein islet-1 modulates estrogen receptor functions". Mol. Endocrinol. 14 (10): 1627-48. 3. Tanizawa Y, Riggs AC, Dagogo-Jack S, Vaxillaire M, Froguel P, Liu L, Donis-Keller H, Permutt MA (July 1994). "Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected]". Diabetes. 43 (7): 935-41.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    ISL1 (ISL LIM Homeobox 1 (ISL1))

    别名

    ISL1

    背景

    Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

    分子量

    50 kDa

    基因ID

    3670

    UniProt

    P61371

    途径

    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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