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PDIA2 抗体 (AA 117-492)

This anti-PDIA2 antibody is a 兔 多克隆 antibody detecting PDIA2 in ELISA, WB 和 FACS. Suitable for 人.
产品编号 ABIN7599783
发货至: 中国

Quick Overview for PDIA2 抗体 (AA 117-492) (ABIN7599783)

抗原

See all PDIA2 抗体
PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDIA2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Flow Cytometry (FACS)
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    AA 117-492

    原理

    Anti-PDIP/PDIA2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PDIP/PDIA2 Antibody Picoband® (ABIN7599783). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PDIP/PDIA2 recombinant protein (Position: Y117-D492).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Desilva, M. G., Lu, J., Donadel, G., Modi, W. S., Xie, H., Notkins, A. L., Lan, M. S. Characterization and chromosomal localization of a new protein disulfide isomerase, PDIp, highly expressed in human pancreas. DNA Cell Biol. 15: 9-16, 1996.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))

    别名

    PDIA2

    背景

    Synonyms: Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130

    Tissue Specificity: Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes.

    Background: Protein disulfide isomerase family A member 2 is a protein that in humans is encoded by the PDIA2 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.

    分子量

    65 kDa

    基因ID

    64714

    UniProt

    Q13087

    途径

    Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response
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