PDIA2 抗体 (AA 117-492)
Quick Overview for PDIA2 抗体 (AA 117-492) (ABIN7599783)
抗原
See all PDIA2 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 117-492
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                                            原理
- Anti-PDIP/PDIA2 Antibody Picoband®
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                                            交叉反应 (详细)
- No cross-reactivity with other proteins.
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                                            产品特性
- Anti-PDIP/PDIA2 Antibody Picoband® (ABIN7599783). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- E.coli-derived human PDIP/PDIA2 recombinant protein (Position: Y117-D492).
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                                            亚型
- IgG
 
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                                            应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
 ELISA, 0.1-0.5 μg/mL, -
 1. Desilva, M. G., Lu, J., Donadel, G., Modi, W. S., Xie, H., Notkins, A. L., Lan, M. S. Characterization and chromosomal localization of a new protein disulfide isomerase, PDIp, highly expressed in human pancreas. DNA Cell Biol. 15: 9-16, 1996.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
 
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    - PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))
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                                            别名
- PDIA2
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                                            背景
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                        Synonyms: Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130 Tissue Specificity: Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes. Background: Protein disulfide isomerase family A member 2 is a protein that in humans is encoded by the PDIA2 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels. 
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                                            分子量
- 65 kDa
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                                            基因ID
- 64714
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                                            UniProt
- Q13087
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                                            途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response
 抗原
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