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PRODH 抗体 (AA 116-433)

This anti-PRODH antibody is a 兔 多克隆 antibody detecting PRODH in WB, ELISA, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599773
发货至: 中国

Quick Overview for PRODH 抗体 (AA 116-433) (ABIN7599773)

抗原

See all PRODH 抗体
PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

适用

人, 小鼠, 大鼠

宿主

  • 48
  • 2
  • 2

克隆类型

  • 50
  • 2
多克隆

标记

  • 23
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PRODH antibody is un-conjugated

应用范围

  • 41
  • 19
  • 13
  • 13
  • 12
  • 6
  • 6
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-433

    原理

    Anti-PRODH Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PRODH Antibody Picoband® (ABIN7599773). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human PRODH recombinant protein (Position: H116-E433).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Afenjar, A., Moutard, M.-L., Doummar, D., Guet, A., Rabier, D., Vermersch, A.-I., Mignot, C., Burglen, L., Heron, D., Thioulouse, E., de Villemeur, T. B., Campion, D., Rodriguez, D. Early neurological phenotype in 4 children with biallelic PRODH mutations. Brain Dev. 29: 547-552, 2007. 2. Baron, M. Genetics of schizophrenia and the new millennium: progress and pitfalls. Am. J. Hum. Genet. 68: 299-312, 2001. 3. Bender, H.-U., Almashanu, S., Steel, G., Hu, C.-A., Lin, W.-W., Willis, A., Pulver, A., Valle, D. Functional consequences of PRODH missense mutations. Am. J. Hum. Genet. 76: 409-420, 2005.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

    别名

    PRODH

    背景

    Synonyms: Peptidyl-prolyl cis-trans isomerase B, PPIase B, 5.2.1.8, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP, PPIB, CYPB,

    Tissue Specificity: Found mainly in the liver, kidney and skeletal muscle.

    Background: Proline dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the PRODH gene. This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    69 kDa

    基因ID

    5625

    UniProt

    O43272

    途径

    Response to Water Deprivation, Monocarboxylic Acid Catabolic Process
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