LIMS1 抗体 (AA 11-172)
Quick Overview for LIMS1 抗体 (AA 11-172) (ABIN7599708)
抗原
See all LIMS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-172
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原理
- Anti-LIMS1 Antibody Picoband®
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产品特性
- Anti-LIMS1 Antibody Picoband® (ABIN7599708). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LIMS1 recombinant protein (Position: E11-A172). Human LIMS1 shares 100% amino acid (aa) sequence identity with mouse LIMS1.
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anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibody
LIMS1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5G7 unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 1-325) antibodyLIMS1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) (AA 68-303) antibodyLIMS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) antibodyLIMS1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Bock-Marquette, I., Saxena, A., White, M. D., DiMaio, J. M., Srivastava, D. Thymosin beta-4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature 432: 466-472, 2004. 2. Chen, K., Tu, Y., Zhang, Z., Blair, H. C., Zhang, L., Wu, C. PINCH-1 regulates the ERK-Bim pathway and contributes to apoptosis resistance in cancer cells. J. Biol. Chem. 283: 2508-2517, 2008. 3. Fukuda, T., Chen, K., Shi, X., Wu, C. PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. J. Biol. Chem. 278: 51324-51333, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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别名
- LIMS1
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背景
- LIM and senescent cell antigen-like-containing domain protein 1 is a protein that in humans is encoded by the LIMS1 gene. The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 37 kDa
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基因ID
- 3987
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UniProt
- P48059
抗原
-
