Clusterin 抗体 (AA 108-320)
Quick Overview for Clusterin 抗体 (AA 108-320) (ABIN7599684)
抗原
See all Clusterin (CLU) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 108-320
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原理
 - Anti-Clusterin/CLU Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-Clusterin/CLU Antibody Picoband® (ABIN7599684). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived human Clusterin/CLU recombinant protein (Position: A108-Q320).
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bertrand, P., Poirier, J., Oda, T., Finch, C. E., Pasinetti, G. M. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Molec. Brain Res. 33: 174-178, 1995. 2. Birkenmeier, E. H., Letts, V. A., Frankel, W. N., Magenheimer, B. S., Calvet, J. P. Sulfated glycoprotein-2 (Sgp-2) maps to mouse chromosome 14. Mammalian Genome 4: 131-132, 1993. Note: Erratum: Mammalian Genome 4: 238 only, 1993. 3. Chen, X., Halberg, R. B., Ehrhardt, W. M., Torrealba, J., Dove, W. F. Clusterin as a biomarker in murine and human intestinal neoplasia. Proc. Nat. Acad. Sci. 100: 9530-9535, 2003. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- Clusterin (CLU)
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别名
 - CLU
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背景
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Synonyms: Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF
Background: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
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分子量
 - 70 kDa
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基因ID
 - 1191
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UniProt
 - P10909
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途径
 - Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
 
抗原
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