Uroplakin 1B 抗体 (AA 107-216)
Quick Overview for Uroplakin 1B 抗体 (AA 107-216) (ABIN7599675)
抗原
See all Uroplakin 1B (UPK1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 107-216
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原理
- Anti-Uroplakin Ib/UPIb Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Uroplakin Ib/UPIb Antibody Picoband® (ABIN7599675). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Uroplakin Ib/UPIb recombinant protein (Position: I107-Q216).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Finch, J. L., Webb, G. C., Evdokiou, A, Cowled, P. A. Chromosomal localization of the human urothelial tetraspan gene, UPK1B, to 3q13.3-q21 and detection of a Taq1 polymorphism. Genomics 40: 501-503, 1997. 2. Lobban, E. D., Smith, B. A., Hall, G. D., Harnden, P., Roberts, P., Selby, P. J., Trejdosiewicz, L. K., Southgate, J. Uroplakin gene expression by normal and neoplastic human urothelium. Am. J. Path. 153: 1957-1967, 1998. 3. Olsburgh, J., Weeks, R., Selby, P., Southgate, J. Human uroplakin 1b gene structure and promoter analysis. Biochim. Biophys. Acta 1576: 163-170, 2002. 4. Webb, G. C., Finch, J. L., Cowled, P. A. Assignment of the uroplakin 1b (Upk1b) gene to mouse chromosome 16 bands B5-C2 by in situ hybridization. Cytogenet. Cell Genet. 84: 37-38, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Uroplakin 1B (UPK1B)
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别名
- UPK1B
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背景
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Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,
Tissue Specificity: Ubiquitous. Highly expressed in brain. .
Background: Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.
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分子量
- 30 kDa
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基因ID
- 7348
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UniProt
- O75841
抗原
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