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Uroplakin 1B 抗体 (AA 107-216)

This anti-Uroplakin 1B antibody is a 兔 多克隆 antibody detecting Uroplakin 1B in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599675
发货至: 中国

Quick Overview for Uroplakin 1B 抗体 (AA 107-216) (ABIN7599675)

抗原

See all Uroplakin 1B (UPK1B) 抗体
Uroplakin 1B (UPK1B)

适用

人, 小鼠, 大鼠

宿主

  • 36
  • 17

克隆类型

  • 36
  • 17
多克隆

标记

  • 22
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
This Uroplakin 1B antibody is un-conjugated

应用范围

  • 38
  • 30
  • 17
  • 16
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 35
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-216

    原理

    Anti-Uroplakin Ib/UPIb Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Uroplakin Ib/UPIb Antibody Picoband® (ABIN7599675). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Uroplakin Ib/UPIb recombinant protein (Position: I107-Q216).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Finch, J. L., Webb, G. C., Evdokiou, A, Cowled, P. A. Chromosomal localization of the human urothelial tetraspan gene, UPK1B, to 3q13.3-q21 and detection of a Taq1 polymorphism. Genomics 40: 501-503, 1997. 2. Lobban, E. D., Smith, B. A., Hall, G. D., Harnden, P., Roberts, P., Selby, P. J., Trejdosiewicz, L. K., Southgate, J. Uroplakin gene expression by normal and neoplastic human urothelium. Am. J. Path. 153: 1957-1967, 1998. 3. Olsburgh, J., Weeks, R., Selby, P., Southgate, J. Human uroplakin 1b gene structure and promoter analysis. Biochim. Biophys. Acta 1576: 163-170, 2002. 4. Webb, G. C., Finch, J. L., Cowled, P. A. Assignment of the uroplakin 1b (Upk1b) gene to mouse chromosome 16 bands B5-C2 by in situ hybridization. Cytogenet. Cell Genet. 84: 37-38, 1999.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Uroplakin 1B (UPK1B)

    别名

    UPK1B

    背景

    Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,

    Tissue Specificity: Ubiquitous. Highly expressed in brain. .

    Background: Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.

    分子量

    30 kDa

    基因ID

    7348

    UniProt

    O75841
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