LEPREL1 抗体 (AA 106-494)
Quick Overview for LEPREL1 抗体 (AA 106-494) (ABIN7599671)
抗原
See all LEPREL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 106-494
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原理
- Anti-P3H2 Antibody Picoband®
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产品特性
- Anti-P3H2 Antibody Picoband® (ABIN7599671). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human P3H2 recombinant protein (Position: E106-R494). Human P3H2 shares 88.9% and 89.5% amino acid (aa) sequence identity with mouse and rat P3H2, respectively.
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anti-Leprecan Like Protein 1 (LEPREL1) (AA 301-528) antibody
LEPREL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leprecan Like Protein 1 (LEPREL1) antibodyLEPREL1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leprecan Like Protein 1 (LEPREL1) antibodyLEPREL1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Leprecan Like Protein 1 (LEPREL1) (AA 400-700) antibodyLEPREL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 10/18/2011. 2. Guo, H., Tong, P., Peng, Y., Wang, T., Liu, Y., Chen, J., Li, Y., Tian, Q., Hu, Y., Zheng, Y., Xiao, L., Xiong, W., Pan, Q., Hu, Z., Xia, K. Homozygous loss-of-function mutation of the LEPREL1 gene causes severe non-syndromic high myopia with early-onset cataract. Clin. Genet. 86: 575-579, 2014. 3. Jarnum, S., Kjellman, C., Darabi, A., Nilsson, I., Edvardsen, K., Aman, P. LEPREL1, a novel ER and Golgi resident member of the Leprecan family. Biochem. Biophys. Res. Commun. 317: 342-351, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- LEPREL1 (Leprecan Like Protein 1 (LEPREL1))
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别名
- P3H2
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背景
- This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 81 kDa
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基因ID
- 55214
抗原
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