LEPREL1 抗体
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北京 101111
Quick Overview for LEPREL1 抗体 (ABIN7230456)
抗原
See all LEPREL1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-P3H2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of P3H2 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human P3H2 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- LEPREL1 (Leprecan Like Protein 1 (LEPREL1))
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别名
- P3H2
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背景
- Prolyl 3-hydroxylase 2, Leprecan-like protein 1, Myxoid liposarcoma-associated protein 4P3H2 gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 77kD
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基因ID
- 55214
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UniProt
- Q8IVL5
抗原
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