Claudin 3 抗体 (AA 101-220)
Quick Overview for Claudin 3 抗体 (AA 101-220) (ABIN7599625)
抗原
See all Claudin 3 (CLDN3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 101-220
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原理
- Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Claudin 3/CLDN3 Antibody Picoband® (monoclonal, 4C7D2) (ABIN7599625). Tested in IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Claudin 3/CLDN3 recombinant protein (Position: A101-V220).
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亚型
- IgG2b
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anti-Claudin 3 (CLDN3) (C-Term) antibody
CLDN3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) antibodyCLDN3 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 181-220) antibodyCLDN3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人, Cow WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 171-220) antibodyCLDN3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 30-159) antibodyCLDN3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (AA 141-220) antibodyCLDN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 3 (CLDN3) (C-Term) antibodyCLDN3 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
1. Coyne, C. B., Gambling, T. M., Boucher, R. C., Carson, J. L., Johnson, L. G. Role of claudin interactions in airway tight junctional permeability. Am. J. Physiol. Lung Cell. Molec. Physiol. 285: L1166-L1178, 2003. 2. Dube, E., Chan, P. T. K., Hermo, L., Cyr, D. G. Gene expression profiling and its relevance to the blood-epididymal barrier in the human epididymis. Biol. Reprod. 76: 1034-1044, 2007. 3. Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K., Tsukita, S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol. 141: 1539-1550, 1998 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Claudin 3 (CLDN3)
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别名
- CLDN3
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背景
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Synonyms: Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, HSPH1, HSP105, HSP110, KIAA0201
Tissue Specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Background: Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
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分子量
- 20 kDa
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基因ID
- 1365
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UniProt
- O15551
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途径
- Hepatitis C
抗原
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