Chloride Channel 5 抗体 (AA 100-756)
Quick Overview for Chloride Channel 5 抗体 (AA 100-756) (ABIN7599619)
抗原
See all Chloride Channel 5 (CLCN5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 100-756
-
原理
- Anti-ClC-5/CLCN5 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-ClC-5/CLCN5 Antibody Picoband® (ABIN7599619). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human CLCN5 recombinant protein (Position: R100-S756).
-
亚型
- IgG
-
-
anti-Chloride Channel 5 (CLCN5) (Middle Region) antibody
CLCN5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) antibodyCLCN5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 15-41), (N-Term) antibodyCLCN5 适用: 人 WB 宿主: 兔 Polyclonal RB42009 unconjugated
anti-Chloride Channel 5 (CLCN5) (Internal Region) antibodyCLCN5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 553-746) antibodyCLCN5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 566-665) antibodyCLCN5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 521-570) antibodyCLCN5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 637-816) antibodyCLCN5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Akuta, N., Lloyd, S. E., Igarashi, T., Shiraga, H., Matsuyama, T., Yokoro, S., Cox, J. P. D., Thakker, R. V. Mutations of CLCN5 in Japanese children with idiopathic low molecular weight proteinuria, hypercalciuria and nephrocalcinosis. Kidney Int. 52: 911-916, 1997. 2. Alex, P., Ye, M., Zachos, N. C., Sipes, J., Nguyen, T., Suhodrev, M., Gonzales, L., Arora, Z., Zhang, T., Centola, M., Guggino, S. E., Li, X. Clcn5 knockout mice exhibit novel immunomodulatory effects and are more susceptible to dextran sulfate sodium-induced colitis. J. Immun. 184: 3988-3996, 2010. 3. Blair, H. J., Ho, M., Monaco, A. P., Fisher, S., Craig, I. W., Boyd, Y. High-resolution comparative mapping of the proximal region of the mouse X chromosome. Genomics 28: 305-310, 1995. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Chloride Channel 5 (CLCN5)
-
别名
- CLCN5
-
背景
-
Synonyms: Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Human mannose receptor, hMR, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1
Tissue Specificity: Ubiquitous.
Background: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
-
分子量
- 100 kDa
-
基因ID
- 1184
-
UniProt
- P51795
抗原
-
