PDE4B 抗体 (AA 1-736)
Quick Overview for PDE4B 抗体 (AA 1-736) (ABIN7599537)
抗原
See all PDE4B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-736
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原理
- Anti-PDE4B Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-PDE4B Antibody Picoband® (ABIN7599537). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDE4B recombinant protein (Position: M1-T736). Human PDE4B shares 96.6% amino acid (aa) sequence identity with rat PDE4B.
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亚型
- IgG
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anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 500-736) antibody
PDE4B 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (C-Term) antibodyVerified PDE4B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 27-215) antibodyPDE4B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (C-Term) antibodyPDE4B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 467-516) antibodyPDE4B 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) antibodyPDE4B 适用: 人, 小鼠 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 62-111) antibodyPDE4B 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, Pig, Bat, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) antibodyPDE4B 适用: 人 ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (N-Term) antibodyPDE4B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4B, cAMP-Specific (PDE4B) (AA 189-217) antibodyPDE4B 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18545 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
ELISA, 0.1-0.5 μg/mL
1. Bolger, G., Michaeli, T., Martins, T., St. John, T., Steiner, B., Rodgers, L., Riggs, M., Wigler, M., Ferguson, K. A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Molec. Cell. Biol. 13: 6558-6571, 1993. 2. Huston, E., Lumb, S., Russell, A., Catterall, C., Ross, A. H., Steele, M. R., Bolger, G. B., Perry, M. J., Owens, R. J., Houslay, M. D. Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3. Biochem. J. 328: 549-558, 1997. 3. Livi, G. P., Kmetz, P., McHale, M. M., Cieslinski, L. B., Sathe, G. M., Taylor, D. P., Davis, R. L., Torphy, T. J., Balcarek, J. M. Cloning and expression of cDNA for a human low-K(m), rolipram-sensitive cyclic AMP phosphodiesterase. Molec. Cell. Biol. 10: 2678-2686, 1990. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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别名
- PDE4B
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背景
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Synonyms: PDE4B, DPDE4, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, EC 3.1.4.53, DPDE4, PDE32
Background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
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分子量
- 83 kDa
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基因ID
- 5142
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UniProt
- Q07343
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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