PKC epsilon 抗体 (AA 1-690)
Quick Overview for PKC epsilon 抗体 (AA 1-690) (ABIN7599526)
抗原
See all PKC epsilon (PRKCE) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-690
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原理
- Anti-PRKCE Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PRKCE Antibody Picoband® (ABIN7599526). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRKCE recombinant protein (Position: M1-K690).
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亚型
- IgG
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anti-Protein Kinase C, epsilon (PRKCE) (AA 631-737) antibody
PRKCE 适用: 人, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 488-737) antibodyPRKCE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 403-672) antibodyPRKCE 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) antibodyPRKCE 适用: 人, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 403-672) antibodyPRKCE 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 53-236) antibodyPRKCE 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 301-400) antibodyPRKCE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, epsilon (PRKCE) (AA 206-236), (N-Term) antibodyPRKCE 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Basta P, Strickland MB, Holmes W, Loomis CR, Ballas LM, Burns DJ (Nov 1992). "Sequence and expression of human protein kinase C-epsilon". Biochim Biophys Acta 1132 (2): 154-60. 2. Knauf, J. A., Elisei, R., Mochly-Rosen, D., Liron, T., Chen, X.-N., Gonsky, R., Korenberg, J. R., Fagin, J. A. Involvement of protein kinase C-epsilon (PKC-epsilon) in thyroid cell death: a truncated chimeric PKC-epsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis. J. Biol. Chem. 274: 23414-23425, 1999. 3. Premkumar, L. S., Ahern, G. P. Induction of vanilloid receptor channel activity by protein kinase C. Nature 408: 985-990, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
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别名
- PRKCE
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背景
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Synonyms: Angiopoietin-related protein 4,Angiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,HFARP,ANGPTL4,ARP4, HFARP, PGAR,PP1158, PSEC0166, UNQ171/PRO197,
Tissue Specificity: Expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney. .
Background: Protein kinase C epsilon type, also known as PKCE, is an enzyme that in humans is encoded by the PRKCE gene. The protein encoded by this gene is one of the PKC family members. PRKCE is mapped to 2p21. This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. It has been found that activation of PRKCE can induce VR1 channel activity at room temperature in the absence of any other agonist. PRKCE gene plays a role in apoptosis signaling pathways in thyroid cells and it has been indicated that a naturally occurring PRKCE mutant that functions as a dominant negative can block cell death triggered by a variety of stimuli. Expression of PRKCE inhibits chemotherapy-induced caspase-3 activation and apoptosis, thereby leading to cell survival.
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分子量
- 94 kDa
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基因ID
- 5581
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UniProt
- Q02156
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途径
- TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
抗原
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