MTA2 抗体 (AA 1-668)
Quick Overview for MTA2 抗体 (AA 1-668) (ABIN7599519)
抗原
See all MTA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-668
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原理
- Anti-MTA2/PID Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MTA2/PID Picoband® Antibody (ABIN7599519). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MTA2/PID recombinant protein (Position: M1-D668).
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亚型
- IgG
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anti-Metastasis Associated 1 Family, Member 2 (MTA2) antibody
MTA2 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 60-180) antibodyMTA2 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, Cow, 马, 兔, 山羊, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 1-394) antibodyMTA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 516-544), (C-Term) antibodyMTA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20031 unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 129-178) antibodyMTA2 适用: 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 398-447) antibodyMTA2 适用: 人, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 380-429) antibodyMTA2 适用: 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, Pig, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cui, Q., Matsusue, K., Toh, Y., Kono, A., Takiguchi, S. Assignment of the metastasis-associated gene (Mta1) to mouse chromosome band 12F and the metastasis-associated gene 2 (Mta2) to mouse chromosome band 19B by fluorescence in situ hybridization. Cytogenet. Cell Genet. 94: 246-247, 2001. 2. Futamura, M., Nishimori, H., Shiratsuchi, T., Saji, S., Nakamura, Y., Tokino, T. Molecular cloning, mapping, and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-associated gene, MTA1. J. Hum. Genet. 44: 52-56, 1999. 3. Luo, J., Su, F., Chen, D., Shiloh, A., Gu, W. Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature 408: 377-381, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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别名
- MTA2
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背景
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Synonyms: Metastasis-associated protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 protein, p53 target protein in deacetylase complex, MTA2, MTA1L1, PID
Tissue Specificity: Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.
Background: Metastasis-associated protein MTA2 is a protein that in humans is encoded by the MTA2 gene. It is mapped to 11q12.3. This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either ly or inly in transcriptional regulation. Their in effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
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分子量
- 75 kDa
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基因ID
- 9219
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UniProt
- O94776
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途径
- Chromatin Binding
抗原
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