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MTA2 抗体 (AA 60-180)

MTA2 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1680913
发货至: 中国
  • 抗原 See all MTA2 抗体
    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
    抗原表位
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-180
    适用
    • 44
    • 32
    • 29
    • 10
    • 9
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    宿主
    • 43
    • 4
    克隆类型
    • 42
    • 5
    多克隆
    标记
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MTA2 antibody is un-conjugated
    应用范围
    • 47
    • 13
    • 10
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    序列
    DSNAREFEEE SKQPGVSEQQ RHQLKHRELF LSRQFESLPA THIRGKCSVT LLNETDILSQ YLEKEDCFFY SLVFDPVQKT LLADQGEIRV GCKYQAEIPD RLVEGESDNR NQQKMEMKVW D
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human MTA2 (NP_004730.2).
    亚型
    IgG
    Top Product
    Discover our top product MTA2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,ChIP,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
    别名
    MTA2 (MTA2 产品)
    别名
    MTA1L1 antibody, PID antibody, fd61b05 antibody, wu:fd61b05 antibody, wu:fi29g02 antibody, zgc:63487 antibody, pid antibody, mta1l1 antibody, MTA2 antibody, DKFZp470E0911 antibody, AW550797 antibody, Mata1l1 antibody, Mta1l1 antibody, mmta2 antibody, metastasis associated 1 family member 2 antibody, metastasis associated 1 family, member 2 antibody, metastasis-associated gene family, member 2 antibody, metastasis associated 1 family member 2 L homeolog antibody, MTA2 antibody, mta2 antibody, Mta2 antibody, mta2.L antibody
    背景
    This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.,MTA2,MTA1L1,PID,Epigenetics & Nuclear Signaling,Chromatin Remodeling,MTA2
    分子量
    55 kDa/75 kDa
    基因ID
    9219
    UniProt
    O94776
    途径
    Chromatin Binding
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