FERMT2 抗体 (AA 1-650)
Quick Overview for FERMT2 抗体 (AA 1-650) (ABIN7599515)
抗原
See all FERMT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-650
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原理
- Anti-Kindlin 2/FERMT2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Kindlin 2/FERMT2 Antibody Picoband® (ABIN7599515). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Kindlin 2/FERMT2 recombinant protein (Position: M1-I650).
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亚型
- IgG
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anti-Fermitin Family Member 2 (FERMT2) antibody
FERMT2 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 14A11 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 1-680) antibodyFERMT2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 155-232) antibodyFERMT2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 380-550) antibodyFERMT2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (C-Term) antibodyFERMT2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fermitin Family Member 2 (FERMT2) (AA 402-451) antibodyFERMT2 适用: 人, Cow, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Rogalski, T. M., Mullen, G. P., Gilbert, M. M., Williams, B. D., Moerman, D. G. The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane. J. Cell Biol. 150: 253-264, 2000. 2. Siegel, D. H., Ashton, G. H. S., Penagos, H. G., Lee, J. V., Feiler, H. S., Wilhelmsen, K. C., South, A. P., Smith, F. J. D., Prescott, A. R., Wessagowit, V., Oyama, N., Akiyama, M., and 30 others. Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am. J. Hum. Genet. 73: 174-187, 2003. 3. Tu, Y., Wu, S., Shi, X., Chen, K., Wu, C. Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. Cell 113: 37-47, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FERMT2 (Fermitin Family Member 2 (FERMT2))
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别名
- FERMT2
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背景
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Synonyms: DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5, CDC46
Tissue Specificity: Ubiquitous.
Background: Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by the FERMT2 gene. Enables several functions, including actin binding activity, phosphatidylinositol-3,4,5-trisphosphate binding activity, and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell differentiation, and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol, focal adhesion, and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia.
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分子量
- 70 kDa
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基因ID
- 10979
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途径
- Cell-Cell Junction Organization
抗原
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