Calpain 6 抗体 (AA 1-641)
Quick Overview for Calpain 6 抗体 (AA 1-641) (ABIN7599511)
抗原
See all Calpain 6 (CAPN6) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-641
-
原理
- Anti-Calpain 6/CAPN6 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Calpain 6-CAPN6 Antibody Picoband® (ABIN7599511). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Calpain 6/CAPN6 recombinant protein (Position: M1-L641). Human Calpain 6/CAPN6 shares 95.2% and 95% amino acid (aa) sequence identity with mouse and rat Calpain 6/CAPN6, respectively.
-
亚型
- IgG
-
-
anti-Calpain 6 (CAPN6) (AA 195-494) antibody
CAPN6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 6 (CAPN6) (Internal Region) antibodyCAPN6 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 6 (CAPN6) antibodyCAPN6 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 5C5 unconjugated
anti-Calpain 6 (CAPN6) (AA 390-419) antibodyCAPN6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19561 unconjugated
anti-Calpain 6 (CAPN6) (C-Term) antibodyCAPN6 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Calpain 6 (CAPN6) (AA 289-319), (Middle Region) antibodyCAPN6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL
1. Dear, N., Matena, K., Vingron, M., Boehm, T. A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution. Genomics 45: 175-184, 1997. 2. Matena, K., Boehm, T., Dear, T. N. Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily. Genomics 48: 117-120, 1998. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Calpain 6 (CAPN6)
-
别名
- CAPN6
-
背景
-
Synonyms: CAPN6, CALPM, CANPX, Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM
Background: Calpain-6 (also known as calpamodulin) is a protein in humans that is encoded by the CAPN6 gene. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
-
分子量
- 75 kDa
-
基因ID
- 827
-
UniProt
- Q9Y6Q1
抗原
-
