Menin 抗体 (AA 1-615)
Quick Overview for Menin 抗体 (AA 1-615) (ABIN7599497)
抗原
See all Menin (MEN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-615
-
原理
- Anti-Menin/MEN1 Antibody
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Menin/MEN1 Antibody (ABIN7599497). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Menin/MEN1 recombinant protein (Position: M1-L615).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
-
别名
- MEN1
-
背景
-
Synonyms: Menin, MEN1, SCG2
Tissue Specificity: Expressed in the islets of Langerhans (at protein level).
Background: Menin is a protein that in humans is encoded by the MEN1 gene. It is mapped to 11q13.1. This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones.
-
分子量
- 70 kDa
-
基因ID
- 4221
-
UniProt
- O00255
-
途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
-