GLS2 抗体 (AA 1-602)
Quick Overview for GLS2 抗体 (AA 1-602) (ABIN7599493)
抗原
See all GLS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-602
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原理
- Anti-GLS2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-GLS2 Antibody Picoband® (ABIN7599493). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GLS2 recombinant protein (Position: M1-V602).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gomez-Fabre, P. M., Aledo, J. C., del Castillo-Olivares, A., Alonso, F. J., Nunez de Castro, I., Campos, J. A., Marquez, J. Molecular cloning, sequencing and expression studies of the human breast cancer cell glutaminase. Biochem. J. 345: 365-375, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))
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别名
- GLS2
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背景
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Synonyms: Cytoskeleton-associated protein 5, Colonic and hepatic tumor overexpressed gene protein, Ch-TOG, CKAP5, KIAA0097
Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.
Background: Glutaminase 2 (liver, mitochondrial) is a protein that in humans is encoded by the GLS2 gene. The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms.
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分子量
- 66 kDa
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基因ID
- 27165
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途径
- Dicarboxylic Acid Transport, Warburg Effect
抗原
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