GLS2 抗体 (Middle Region)
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北京 101111
Quick Overview for GLS2 抗体 (Middle Region) (ABIN2781319)
抗原
See all GLS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- GLS2 Antibody - middle region
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序列
- FVGKEPSGLR YNKLSLNEEG IPHNPMVNAG AIVVSSLIKM DCNKAEKFDF
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against GLS2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human GLS2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101632
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
: "Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1387-96, (2012) (PubMed).
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- GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))
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别名
- GLS2
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背景
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Background Information: GLS2 is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well.
Gene Name: Glutaminase 2 (liver, mitochondrial)
Alternative Symbols: GA, GLS, LGA, hLGA
Protein Name: Glutaminase liver isoform, mitochondrial
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分子量
- 36kDa
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基因ID
- 27165
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UniProt
- Q9UI32
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途径
- Dicarboxylic Acid Transport, Warburg Effect
抗原
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