ME1 抗体 (AA 1-572)
Quick Overview for ME1 抗体 (AA 1-572) (ABIN7599485)
抗原
See all ME1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-572
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原理
- Anti-ME1 Antibody Picoband® (monoclonal, 5E5F7)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ME1 Antibody Picoband® (monoclonal, 5E5F7) (ABIN7599485). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ME1 recombinant protein (Position: M1-Q572).
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亚型
- IgG1
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anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibody
ME1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) antibodyKO Validated ME1 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 161-519) antibodyME1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (C-Term) antibodyME1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (N-Term) antibodyME1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 绵羊, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 37-70) antibodyME1 适用: 人 WB 宿主: 兔 Polyclonal RB55906 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 36-85) antibodyME1 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-300) antibodyME1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
1. Chen, T.-R., McMorris, F. A., Creagan, R., Ricciuti, F. C., Tischfield, J., Ruddle, F. H. Assignment of the genes for malate oxidoreductase decarboxylating to chromosome 6 and peptidase B and lactate dehydrogenase B to chromosome 12 in man. Am. J. Hum. Genet. 25: 200-207, 1973. 2. Cohen, P. T. W., Omenn, G. S. Genetic variation of the cytoplasmic and mitochondrial malic enzymes in the monkey: Macaca nemestrina. Biochem. Genet. 7: 289-301, 1972. 3. Gimelbrant, A., Hutchinson, J. N., Thompson, B. R., Chess, A. Widespread monoallelic expression on human autosomes. Science 318: 1136-1140, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
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别名
- ME1
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背景
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Synonyms: Survival motor neuron protein, Component of gems 1, Gemin-1, SMN1, SMN, SMNT, SMN2, SMNC
Tissue Specificity: Expressed in a wide variety of tissues. Expressed at high levels in brain, kidney and liver, moderate levels in skeletal and cardiac muscle, and low levels in fibroblasts and lymphocytes. Also seen at high levels in spinal cord. Present in osteoclasts and mononuclear cells (at protein level).
Background: NADP-dependent malic enzyme is a protein that in humans is encoded by the ME1 gene. This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
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分子量
- 64 kDa
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基因ID
- 4199
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UniProt
- P48163
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途径
- Regulation of Lipid Metabolism by PPARalpha
抗原
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