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ME1 抗体 (N-Term)

The 兔 多克隆 anti-ME1 antibody (ABIN2777597) specifically detects ME1 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 兔, 马, Pig, 绵羊 和 Cow samples.
产品编号 ABIN2777597
发货至: 中国
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Quick Overview for ME1 抗体 (N-Term) (ABIN2777597)

抗原

See all ME1 抗体
ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

适用

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人, 小鼠, 大鼠, 犬, 兔, 马, Pig, 绵羊, Cow

宿主

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兔

克隆类型

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多克隆

标记

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This ME1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    ME1 Antibody - N-terminal region

    序列

    QQLNIHGLLP PSFNSQEIQV LRVVKNFEHL NSDFDRYLLL MDLQDRNEKL

    预测反应

    Cow: 92%, Dog: 85%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 91%, Rabbit: 100%, Rat: 100%, Sheep: 92%

    产品特性

    This is a rabbit polyclonal antibody against ME1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ME1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104821

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

    别名

    ME1

    背景

    Background Information: ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Malic enzyme 1, NADP(+)-dependent, cytosolic

    Alternative Symbols: MES, HUMNDME

    Protein Name: NADP-dependent malic enzyme

    分子量

    64kDa

    基因ID

    4199

    NCBI登录号

    NP_002386

    UniProt

    P48163

    途径

    Regulation of Lipid Metabolism by PPARalpha
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