FANCC 抗体 (AA 1-558)
Quick Overview for FANCC 抗体 (AA 1-558) (ABIN7599476)
抗原
See all FANCC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-558
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原理
- Anti-FANCC Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FANCC Antibody Picoband® (ABIN7599476). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FANCC recombinant protein (Position: M1-V558).
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亚型
- IgG
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anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 319-558) antibody
FANCC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-558) antibodyFANCC 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (Center) antibodyFANCC 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-210) antibodyFANCC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-100) antibodyFANCC 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6E7 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (C-Term) antibodyFANCC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 527-555), (C-Term) antibodyFANCC 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24076 unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 529-558), (C-Term) antibodyFANCC 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (N-Term) antibodyFANCC 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group C (FANCC) (AA 1-558) antibodyFANCC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, M., Tomkins, D. J., Auerbach, W., McKerlie, C., Youssoufian, H., Liu, L., Gan, O., Carreau, M., Auerbach, A., Groves, T., Guidos, C. J., Freedman, M. H., Cross, J., Percy, D. H., Dick, J. E., Joyner, A. L., Buchwald, M. Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nature Genet. 12: 448-451, 1996. 2. Donahue, S. L., Campbell, C. A DNA double strand break repair defect in Fanconi anemia fibroblasts. J. Biol. Chem. 277: 46243-46247, 2002. 3. Garcia-Higuera, I., Kuang, Y., Naf, D., Wasik, J., D'Andrea, A. D. Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. Molec. Cell. Biol. 19: 4866-4873, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FANCC (Fanconi Anemia, Complementation Group C (FANCC))
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别名
- FANCC
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背景
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Synonyms: Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12, CASP2, ICH1, NEDD2
Tissue Specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Background: Fanconi anemia group C protein is a protein that in humans is encoded by the FANCC gene. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.
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分子量
- 63 kDa
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基因ID
- 2176
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UniProt
- Q00597
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途径
- DNA Damage Repair
抗原
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