GFI1 抗体 (AA 1-422)
Quick Overview for GFI1 抗体 (AA 1-422) (ABIN7599380)
抗原
See all GFI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-422
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原理
- Anti-GFI1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GFI1 Antibody Picoband® (ABIN7599380). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GFI1 recombinant protein (Position: M1-K422).
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亚型
- IgG
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anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibody
GFI1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D7 unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibodyGFI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 280-330) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-422) antibodyGFI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 32-81) antibodyGFI1 适用: 人, 大鼠, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bell, D. W., Taguchi, T., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Gilks, C. B., Zweidler-McKay, P., Grimes, H. L., Tsichlis, P. N., Testa, J. R. Chromosomal localization of a gene, GFI1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents. Cytogenet. Cell Genet. 70: 263-267, 1995. 2. Duan, Z., Horwitz, M. Targets of the transcriptional repressor oncoprotein Gfi-1. Proc. Nat. Acad. Sci. 100: 5932-5937, 2003. Note: Erratum: Proc. Nat. Acad. Sci. 108: 16134 only, 2011. 3. Gilks, C. B., Bear, S. E., Grimes, H. L., Tsichlis, P. N. Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi1) encoding a novel zinc finger protein. Molec. Cell Biol. 13: 1759-1768, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GFI1 (Growth Factor Independent 1 (GFI1))
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别名
- GFI1
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背景
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Synonyms: Zinc finger protein Gfi-1, Growth factor independent protein 1, Zinc finger protein 163, GFI1, ZNF163
Tissue Specificity: Isoform 1 is expressed in pancreas. Isoform 2 and isoform 3 is expressed in liver.
Background: Zinc finger protein Gfi-1 is a transcriptional repressor that in humans is encoded by the GFI1 gene. It is mapped to 1p22.1. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
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分子量
- 55 kDa
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基因ID
- 2672
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UniProt
- Q99684
抗原
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