IFT74 抗体 (AA 1-375)
Quick Overview for IFT74 抗体 (AA 1-375) (ABIN7599323)
抗原
See all IFT74 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-375
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原理
- Anti-IFT74 Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-IFT74 Antibody Picoband® (ABIN7599323). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PELI3 recombinant protein (Position: M1-R375). Human PELI3 shares 90.1% amino acid (aa) sequence identity with mouse PELI3.
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亚型
- IgG
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anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (C-Term) antibody
Verified IFT74 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) antibodyVerified IFT74 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (AA 1-100) antibodyIFT74 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (C-Term) antibodyIFT74 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (AA 51-150) antibodyIFT74 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (AA 375-600) antibodyIFT74 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (AA 1-100) antibodyIFT74 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (C-Term) antibody (Biotin)Verified IFT74 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal Biotin
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) antibodyIFT74 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport Protein 74 Homolog (IFT74) (AA 1-372) antibodyIFT74 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bell, S. E., Mavila, A., Salazar, R., Bayless, K. J., Kanagala, S., Maxwell, S. A., Davis, G. E. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. J. Cell Sci. 114: 2755-2773, 2001. 2. Bhogaraju, S., Cajanek, L., Fort, C., Blisnick, T., Weber, K., Taschner, M., Mizuno, N., Lamla, S., Bastin, P., Nigg, E. A., Lorentzen, E. Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. Science 341: 1009-1012, 2013. 3. Ezratty, E. J., Stokes, N., Chai, S., Shah, A. S., Williams, S. E., Fuchs, E. A role for the primary cilium in Notch signaling and epidermal differentiation during skin development. Cell 145: 1129-1141, 2011. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IFT74 (Intraflagellar Transport Protein 74 Homolog (IFT74))
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别名
- IFT74
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.
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分子量
- 69 kDa
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基因ID
- 80173
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途径
- Hedgehog Signaling, Chromatin Binding
抗原
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