DTNBP1 抗体 (AA 1-351)
Quick Overview for DTNBP1 抗体 (AA 1-351) (ABIN7599300)
抗原
See all DTNBP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-351
-
原理
- Anti-Dysbindin/DTNBP1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Dysbindin/DTNBP1 Antibody Picoband® (ABIN7599300). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Dysbindin/DTNBP1 recombinant protein (Position: M1-S351). Human Dysbindin/DTNBP1 shares 79.4% and 78.6% amino acid (aa) sequence identity with mouse and rat Dysbindin/DTNBP1, respectively.
-
亚型
- IgG
-
-
anti-Dystrobrevin Binding Protein 1 (DTNBP1) antibody
DTNBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 258-351) antibodyDTNBP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 179-319) antibodyDTNBP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-100) antibodyDTNBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (C-Term) antibodyDTNBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 1-351) antibodyDTNBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) antibodyDTNBP1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 110-305) antibodyDTNBP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) antibodyDTNBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 101-200) antibodyDTNBP1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Benson, M. A., Newey, S. E., Martin-Rendon, E., Hawkes, R., Blake, D. J. Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain. J. Biol. Chem. 276: 24232-24241, 2001. 2. Bryan, M. M., Tolman, N. J., Simon, K. L., Huizing, M., Hufnagel, R. B., Brooks, B. P., Speransky, V., Mullikin, J. C., Gahl, W. A., Malicdan, M. C. V., Gochuico, B. R. Clinical and molecular phenotyping of a child with Hermansky-Pudlak syndrome-7, an uncommon genetic type of HPS. Molec. Genet. Metab. 120: 378-383, 2017. 3. Dickman, D. K., Davis, G. W. The schizophrenia susceptibility gene dysbindin controls synaptic homeostasis. Science 326: 1127-1130, 2009. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
-
别名
- DTNBP1
-
背景
-
Synonyms: DTNBP1, BLOC1S8, My031, Dysbindin, Biogenesis of lysosome-related organelles complex 1 subunit 8, BLOC-1 subunit 8, Dysbindin-1, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein, HPS7 protein
Background: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
-
分子量
- 50 kDa
-
基因ID
- 84062
-
途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-
