电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

DTNBP1 抗体 (AA 101-200)

DTNBP1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN731363
发货至: 中国
  • 抗原 See all DTNBP1 抗体
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    抗原表位
    • 14
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 59
    • 28
    • 26
    • 15
    • 1
    • 1
    大鼠
    宿主
    • 88
    • 2
    克隆类型
    • 88
    • 2
    多克隆
    标记
    • 26
    • 9
    • 9
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This DTNBP1 antibody is un-conjugated
    应用范围
    • 47
    • 42
    • 30
    • 25
    • 25
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Cow,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DTNBP1
    亚型
    IgG
    Top Product
    Discover our top product DTNBP1 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    别名
    DTNBP1 (DTNBP1 产品)
    别名
    5430437B18Rik antibody, AW048963 antibody, Bloc1s8 antibody, dysbindin antibody, sdy antibody, BLOC1S8 antibody, DBND antibody, HPS7 antibody, My031 antibody, SDY antibody, dtnbp1 antibody, zgc:56462 antibody, MGC83903 antibody, dbnd antibody, hps7 antibody, my031 antibody, MGC85477 antibody, DTNBP1 antibody, CG6856 antibody, Ddysb antibody, Dmel\\CG6856 antibody, si:ch211-285p6.1 antibody, dystrobrevin binding protein 1 antibody, Dysbindin antibody, dystrobrevin binding protein 1a antibody, dystrobrevin binding protein 1 L homeolog antibody, dystrobrevin binding protein 1 S homeolog antibody, dystrobrevin binding protein 1b antibody, Dtnbp1 antibody, DTNBP1 antibody, dtbp1 antibody, dtnbp1a antibody, dtnbp1.L antibody, dtnbp1.S antibody, dtnbp1 antibody, Dysb antibody, dtnbp1b antibody
    背景

    Synonyms: SDY, DBND, HPS7, My031, BLOC1S8, Dysbindin, Biogenesis of lysosome-related organelles complex 1 subunit 8, BLOC-1 subunit 8, Dysbindin-1, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein, HPS7 protein, DTNBP1

    Background: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.

    基因ID
    84062
    UniProt
    Q96EV8
    途径
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
You are here:
客服