RNF2 抗体 (AA 1-336)
Quick Overview for RNF2 抗体 (AA 1-336) (ABIN7599286)
抗原
See all RNF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-336
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原理
- Anti-RING2/RING1B/RNF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RING2/RING1B/RNF2 Antibody Picoband® (ABIN7599286). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RING2/RING1B/RNF2 recombinant protein (Position: M1-K336).
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亚型
- IgG
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anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibody
RNF2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibodyRNF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-336) antibodyRNF2 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 164-223) antibodyRNF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Ring Finger Protein 2 (RNF2) (Middle Region) antibodyRNF2 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 198-232) antibodyRNF2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB52337 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-100) antibodyRNF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 165-199) antibodyRNF2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB52402 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: RNF2 ring finger protein 2". 2. Lee SJ, Choi JY, Sung YM, Park H, Rhim H, Kang S (August 2001). "E3 ligase activity of RING finger proteins that interact with Hip-2, a human ubiquitin-conjugating enzyme". FEBS Lett 503 (1): 61-4. 3. Tuckfield, Annabel, Clouston David R, Wilanowski Tomasz M, Zhao Lin-Lin, Cunningham John M, Jane Stephen M (March 2002). "Binding of the RING polycomb proteins to specific target genes in complex with the grainyhead-like family of developmental transcription factors". Mol. Cell. Biol. (United States) 22 (6): 1936-46. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RNF2 (Ring Finger Protein 2 (RNF2))
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别名
- RNF2
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背景
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Synonyms: Vinculin, Metavinculin, MV, VCL
Tissue Specificity: Metavinculin is muscle-specific.
Background: E3 ubiquitin-protein ligase RING2 is an enzyme that in humans is encoded by the RNF2 gene. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
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分子量
- 38 kDa
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基因ID
- 6045
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UniProt
- Q99496
抗原
-
