ONECUT1 抗体 (AA 1-270)
Quick Overview for ONECUT1 抗体 (AA 1-270) (ABIN7599190)
抗原
See all ONECUT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-270
-
原理
- Anti-ONECUT1 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-ONECUT1 Antibody Picoband® (ABIN7599190). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human ONECUT1 recombinant protein (Position: M1-E270).
-
亚型
- IgG
-
-
anti-One Cut Homeobox 1 (ONECUT1) (AA 187-203), (N-Term) antibody
ONECUT1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (C-Term) antibodyONECUT1 适用: 人, 大鼠, 犬, 兔, Pig, 马, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (C-Term) antibodyONECUT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (AA 192-292) antibodyONECUT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (AA 420-470) antibodyONECUT1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (Middle Region) antibodyONECUT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (AA 85-198) antibodyONECUT1 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (N-Term) antibodyONECUT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (AA 370-419) antibodyONECUT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 豚鼠, 马, 斑马鱼, Bat, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-One Cut Homeobox 1 (ONECUT1) (N-Term) antibodyONECUT1 适用: 人, 犬, 兔, Cow, Pig, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Jacquemin, P., Durviaux, S. M., Jensen, J., Godfraind, C., Gradwohl, G., Guillemot, F., Madsen, O. D., Carmeliet, P., Dewerchin, M., Collen, D., Rousseau, G. G., Lemaigre, F. P. Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3. Molec. Cell. Biol. 20: 4445-4454, 2000. 2. Maestro, M. A., Boj, S. F., Luco, R. F., Pierreux, C. E., Cabedo, J., Servitja, J. M., German, M. S., Rousseau, G. G., Lemaigre, F. P., Ferrer, J. Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas. Hum. Molec. Genet. 12: 3307-3314, 2003. 3. Samadani, U., Costa, R. H. The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression. Molec. Cell. Biol. 16: 6273-6284, 1996. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- ONECUT1 (One Cut Homeobox 1 (ONECUT1))
-
别名
- ONECUT1
-
背景
-
Synonyms: Mesoderm posterior protein 1, Class C basic helix-loop-helix protein 5, bHLHc5, MESP1, BHLHC5
Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .
Background: One cut homeobox 1(ONECUT1), also called Hepatocyte nuclear factor 6(HNF6) is found strong expression in liver and lower expression in testis and skin. ONECUT1 gene is mapped to 15q21.3. This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer.
-
分子量
- 50 kDa
-
基因ID
- 3175
抗原
-
