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ONECUT1 抗体 (Middle Region)

ONECUT1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780599
发货至: 中国
  • 抗原 See all ONECUT1 抗体
    ONECUT1 (One Cut Homeobox 1 (ONECUT1))
    抗原表位
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 20
    • 19
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马, 斑马鱼
    宿主
    • 45
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 24
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ONECUT1 antibody is un-conjugated
    应用范围
    • 36
    • 24
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ITISQQLGLE LSTVSNFFMN ARRRSLDKWQ DEGSSNSGNS SSSSSTCTKA
    预测反应
    Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against ONECUT1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1
    Top Product
    Discover our top product ONECUT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 465 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yuan, Wang, Hu, Tang, Shi, Guo, Song: "Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 31206-16, (2013) (PubMed).

    Huang, Mei, Yu, Zhang, Han, Jiang, Zhou: "Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig." in: Acta histochemica, Vol. 111, Issue 2, pp. 157-65, (2009) (PubMed).

  • 抗原
    ONECUT1 (One Cut Homeobox 1 (ONECUT1))
    别名
    ONECUT1 (ONECUT1 产品)
    别名
    D9Ertd423e antibody, HNF-6 antibody, Hfh12 antibody, Hnf6 antibody, Hnf6b antibody, OC-1 antibody, Oc1 antibody, onecut antibody, onecut1 antibody, id:ibd5005 antibody, HNF6 antibody, HNF6A antibody, HNF-6a antibody, oc1 antibody, onecut1l antibody, zgc:65904 antibody, zgc:77450 antibody, one cut domain, family member 1 antibody, one cut homeobox 1 antibody, one cut domain, family member, like antibody, Onecut1 antibody, onecutl antibody, ONECUT1 antibody, onecut1 antibody
    背景
    ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
    Alias Symbols: HNF-6, HNF6, HNF6A
    Protein Interaction Partner: NR0B2, KAT2B, FOXA2, CREBBP, NR3C1, FOXA1,
    Protein Size: 465
    分子量
    51 kDa
    基因ID
    3175
    NCBI登录号
    NM_004498, NP_004489
    UniProt
    Q9UBC0
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