RAD17 抗体 (AA 1-267)
Quick Overview for RAD17 抗体 (AA 1-267) (ABIN7599188)
抗原
See all RAD17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-267
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原理
- Anti-Rad17 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Rad17 Antibody (ABIN7599188). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Rad17 recombinant protein (Position: M1-Q267).
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亚型
- IgG
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anti-RAD17 (RAD17) (AA 1-584) antibody
RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 391-670) antibodyRAD17 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 1-110) antibodyRAD17 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-RAD17 (RAD17) (AA 1-270) antibodyRAD17 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) antibodyKD Validated RAD17 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (C-Term) antibodyRAD17 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) (AA 621-670) antibodyRAD17 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD17 (RAD17) antibodyRAD17 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 3-10E-010 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAD17
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别名
- Rad17
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背景
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Synonyms: T-cell surface glycoprotein CD1b, CD1b, CD1B
Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.
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分子量
- 77 kDa
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基因ID
- 19356
抗原
-
