GRB10 抗体 (AA 1-251)
Quick Overview for GRB10 抗体 (AA 1-251) (ABIN7599161)
抗原
See all GRB10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-251
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原理
- Anti-GRB10 Antibody (monoclonal, 5H7)
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-GRB10 Antibody (monoclonal, 5H7) (ABIN7599161). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Monkey, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GRB10 recombinant protein (Position: M1-K251).
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亚型
- IgG1
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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别名
- GRB10
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背景
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Synonyms: Deoxycytidine kinase, dCK, DCK
Tissue Specificity: Expressed ubiquitously in normal tissues.
Background: GRB10, Growth factor receptor-bound protein 10, also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors (e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.
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分子量
- 67 kDa
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基因ID
- 2887
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UniProt
- Q13322
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途径
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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