NQO2 抗体 (AA 1-231)
Quick Overview for NQO2 抗体 (AA 1-231) (ABIN7599124)
抗原
See all NQO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-231
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原理
- Anti-NQO2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NQO2 Antibody Picoband® (ABIN7599124). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NQO2 recombinant protein (Position: M1-Q231).
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亚型
- IgG
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anti-NQO2 (NQO2) antibody
NQO2 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-NQO2 (NQO2) (AA 1-231) antibodyNQO2 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-NQO2 (NQO2) (Center) antibodyNQO2 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-NQO2 (NQO2) antibodyNQO2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NQO2 (NQO2) antibodyNQO2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NQO2 (NQO2) (AA 1-231) antibodyNQO2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-NQO2 (NQO2) (N-Term) antibodyNQO2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NQO2 (NQO2) (AA 21-52) antibodyNQO2 适用: 人 WB 宿主: 兔 Polyclonal RB53881 unconjugated
anti-NQO2 (NQO2) (AA 1-231) antibodyNQO2 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NQO2 (NQO2) antibodyNQO2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal AT1E3 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gaikwad, N. W., Yang, L., Rogan, E. G., Cavalieri, E. L. Evidence for NQO2-mediated reduction of the carcinogenic estrogen ortho-quinones. Free Radic. Biol. Med. 46: 253-262, 2009. 2. Jaiswal, A. K., Bell, D. W., Radjendirane, V., Testa, J. R. Localization of human NQO1 gene to chromosome 16q22 and NQO2-6p25 and associated polymorphisms. Pharmacogenetics 9: 413-418, 1999. 3. Jaiswal, A. K., Burnett, P., Adesnik, M., McBride, O. W. Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family: extensive polymorphism at the NQO2 gene locus on chromosome 6. (Abstract) Biochemistry 29: 1899-1906, 1990. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NQO2
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别名
- NQO2
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背景
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Synonyms: General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, Basic transcription factor 2 89 kDa subunit, BTF2 p89, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, TFIIH basal transcription factor complex 89 kDa subunit, TFIIH 89 kDa subunit, TFIIH p89, Xeroderma pigmentosum group B-complementing protein, ERCC3, XPB, XPBC
Tissue Specificity: Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes. Isoform v1 is expressed in spleen. Isoform v2 is expressed in testis. Also detected in ovary, placenta, pancreas, cardiac fibroblasts. Expressed in B-cells and prostate malignant cells. Isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells. Isoform v2 and isoform v4 are expressed in endothelial cells. Isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells. Isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
Background: NAD(P)H dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
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分子量
- 26 kDa
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基因ID
- 4835
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UniProt
- P16083
抗原
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