BRD2 抗体 (AA 1-214)
Quick Overview for BRD2 抗体 (AA 1-214) (ABIN7599091)
抗原
See all BRD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-214
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原理
- Anti-BRD2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BRD2 Antibody Picoband® (ABIN7599091). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BRD2 recombinant protein (Position: M1-Q214).
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亚型
- IgG
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anti-Bromodomain Containing 2 (BRD2) (AA 227-364) antibody
BRD2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7C1B10 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 167-256) antibodyBRD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 227-364) antibodyBRD2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H6B12 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 1-801) antibodyBRD2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 170-200) antibodyBRD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3416 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 1-801) antibodyBRD2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (C-Term) antibodyBRD2 适用: 人, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) antibodyBRD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (Internal Region) antibodyBRD2 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (Middle Region) antibodyBRD2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Beck, S., Hanson, I., Kelly, A., Pappin, D. J., Trowsdale, J. A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC. DNA Seq. 2: 203-210, 1992. 2. Dawson, M. A., Prinjha, R. K., Dittmann, A., Giotopoulos, G., Bantscheff, M., Chan, W.-I., Robson, S. C., Chung, C., Hopf, C., Savitski, M. M., Huthmacher, C., Gudgin, E., and 15 others. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 478: 529-533, 2011. 3. Denis, G. V., Green, M. R. A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator. Genes Dev. 10: 261-271, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- BRD2 (Bromodomain Containing 2 (BRD2))
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别名
- BRD2
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背景
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Synonyms: Bromodomain-containing protein 2, O27.1.1, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3
Tissue Specificity: Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.
Background: Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. It is mapped to 6p21.32. This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
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分子量
- 110 kDa
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基因ID
- 6046
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UniProt
- P25440
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途径
- Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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