BAG2 抗体 (AA 1-211)
Quick Overview for BAG2 抗体 (AA 1-211) (ABIN7599087)
抗原
See all BAG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-211
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原理
- Anti-BAG2 Antibody Picoband® (monoclonal, 8F11G2)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BAG2 Antibody Picoband® (monoclonal, 8F11G2) (ABIN7599087). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BAG2 recombinant protein (Position: M1-N211). Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.
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亚型
- IgG1
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anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody
BAG2 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) antibodyBAG2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 1-211) antibodyBAG2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 1-211) antibodyBAG2 适用: 人 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibodyVerified BAG2 适用: 人, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 102-211) antibodyBAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E12 unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibodyBAG2 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, Pig, Cow, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) antibodyKO Validated BAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibodyBAG2 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 148-176), (C-Term) antibodyBAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34133 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Takayama S, Xie Z, Reed JC (Feb 1999). "An evolutionarily conserved family of Hsp70/Hsc70 Molecular chaperone regulators". J Biol Chem 274 (2): 781-6. 2. "Entrez Gene: BAG2 BCL2-associated athanogene 2". -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
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别名
- BAG2
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背景
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Synonyms: Cofilin-2, Cofilin, muscle isoform, CFL2
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Background: BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.
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分子量
- 24 kDa
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基因ID
- 9532
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UniProt
- O95816
抗原
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