我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

BAG2 抗体 (C-Term)

Name: BAG2 抗体 (C-Term)
SKU: ABIN2775278
Availability: OutOfStock

BAG2 适用: 人, 大鼠, 小鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated

WB Suggested Anti-BAG2 Antibody Titration: 1. (BAG2 抗体 (C-Term))

Rabbit Anti-BAG2 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (BAG2 抗体 (C-Term))

IHC

Sample Type: Lane 1:241 µg untransfected human Saos2 cells Lane 2: 041 µg siRUVBL transfected human Saos2 cells Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:0000 Color/Signal Descriptions: BAG2 Gene Name: Wenwei Hu, Xuetian Yue, Rutgers Cancer Institute of New Jersey. (BAG2 抗体 (C-Term))

Host: Rabbit Target Name: BAG2 Sample Tissue: Human HepG2 Antibody Dilution: 1. (BAG2 抗体 (C-Term))

5 images

(1 reference)

产品编号 ABIN2775278

发货至: 中国

Datasheet as PDF

抗原 See all BAG2 抗体

BAG2 (BCL2-Associated Athanogene 2 (BAG2))
抗原表位
15

14

10

5

2

2

2

1

1
C-Term
适用
53

25

10

2

2

2

2

2

1

1

1

1

1
人, 大鼠, 小鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马
宿主
49

5

1
兔
Compatible Secondaries
克隆类型
50

4
多克隆
标记
31

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
This BAG2 antibody is un-conjugated
应用范围
51

25

20

13

13

9

3

2

2

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEHSKGAGSK

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against BAG2. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human BAG2
anti-BCL2-Associated Athanogene 2 (BAG2) antibody
BAG2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) (AA 1-211) antibody
BAG2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) antibody
BAG2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) (AA 1-211) antibody
BAG2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) antibody
BAG2 适用: 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) (AA 102-211) antibody
BAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E12 unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody
BAG2 适用: 人, 大鼠, 小鼠, 犬, 兔, 斑马鱼, Pig, Cow, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody
Verified BAG2 适用: 人, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) antibody
KO Validated BAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated Athanogene 2 (BAG2) (AA 148-176), (C-Term) antibody
BAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34133 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 211 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Yue, Zhao, Liu, Zhang, Yu, Wang, Zheng, Liu, Li, Feng, Hu: "BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function." in: eLife, Vol. 4, (2015) (PubMed).
抗原

BAG2 (BCL2-Associated Athanogene 2 (BAG2))

别名

BAG2 (BAG2 产品)

别名

bag2 antibody, MGC89300 antibody, BAG2 antibody, ATBAG2 antibody, BCL-2-associated athanogene 2 antibody, MTG10.13 antibody, MTG10_13 antibody, BAG-2 antibody, dJ417I1.2 antibody, zgc:64195 antibody, 2610042A13Rik antibody, BC016230 antibody, BCL2 associated athanogene 2 antibody, BCL-2-associated athanogene 2 antibody, BCL2-associated athanogene 2 antibody, Bcl2-associated athanogene 2 antibody, bag2 antibody, BAG2 antibody, Bag2 antibody

背景

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Alias Symbols: RP3-496N17.2, BAG-2, KIAA0576, MGC149462, dJ417I1.2
Protein Interaction Partner: BAG2, UBC, TP53, LGALS3BP, TUBGCP2, TUBG1, STIP1, TAB1, STUB1, DNAJB6, MLF2, TTC1, STXBP2, SGTA, DNAJB1, HSPA8, SHFM1, PINK1, RPA3, RPA2, RPA1, AHNAK, PARK2, LATS2, TARDBP, EGFR, BAG3, HDAC11, SOX2, NPM1, PAN2, WDR83, WDR77, CCAR2, METTL21B, DNAJC6, NOS2,
Protein Size: 211

分子量

23 kDa

基因ID

9532

NCBI登录号

NM_004282, NP_004273

UniProt

O95816