Myosin 抗体 (AA 1-1895)
Quick Overview for Myosin 抗体 (AA 1-1895) (ABIN7599054)
抗原
See all Myosin 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-1895
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原理
- Anti-MYH14 Antibody Picoband®
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产品特性
- Anti-MYH14 Antibody Picoband® (ABIN7599054). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MYH14 recombinant protein (Position: M1-R1895). Human MYH14 shares 92.5% amino acid (aa) sequence identity with mouse MYH14.
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anti-Myosin (AA 1069-1331) antibody
适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin (AA 1058-1195) antibody适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin (AA 654-668) antibody适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47185 unconjugated
anti-Myosin (Internal Region) antibody适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin (Internal Region) antibody适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin (AA 12-27) antibody适用: 人, 小鼠, 大鼠, Avian, 哺乳动物 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myosin (Internal Region) antibody适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Choi, B.-O., Kang, S. H., Hyun, Y. S., Kanwal, S., Park, S. W., Koo, H., Kim, S.-B., Choi, Y.-C., Yoo, J. H., Kim, J.-W., Park, K. D., Choi, K.-G., Kim, S. J., Zuchner, S., Chung, K. W. A complex phenotype of peripheral neuropathy, myopathy, hoarseness, and hearing loss is linked to an autosomal dominant mutation in MYH14. Hum. Mutat. 32: 669-677, 2011. 2. Donaudy, F., Snoeckx, R., Pfister, M., Zenner, H.-P., Blin, N., Di Stazio, M., Ferrara, A., Lanzara, C., Ficarella, R., Declau, F., Pusch, C. M., Nurnberg, P., Melchionda, S., Zelante, L., Ballana, E., Estivill, X., Van Camp, G., Gasparini, P., Savoia, A. Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and mutated in patients affected by autosomal dominant hearing impairment (DFNA4). Am. J. Hum. Genet. 74: 770-776, 2004. 3. Golomb, E., Ma, X., Jana, S. S., Preston, Y. A., Kawamoto, S., Shoham, N. G., Goldin, E., Conti, M. A., Sellers, J. R., Adelstein, R. S. Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J. Biol. Chem. 279: 2800-2808, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Myosin
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别名
- MYH14
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背景
- Myosin-14 is a protein that in humans is encoded by the MYH14 gene. This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin, it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 250 kDa
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基因ID
- 79784
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UniProt
- Q7Z406
抗原
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