ITGB3BP 抗体 (AA 1-177)
Quick Overview for ITGB3BP 抗体 (AA 1-177) (ABIN7599037)
抗原
See all ITGB3BP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-177
-
原理
- Anti-Centromere protein R/ITGB3BP Antibody Picoband®
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
产品特性
- Anti-Centromere protein R/ITGB3BP Antibody Picoband® (ABIN7599037). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Centromere protein R/ITGB3BP recombinant protein (Position: M1-N177). Human ITGB3BP shares 94.4% and 59.8% amino acid (aa) sequence identity with mouse and rat ITGB3BP, respectively.
-
亚型
- IgG
-
-
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-100) antibody
ITGB3BP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-177) antibodyITGB3BP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (Internal Region) antibodyITGB3BP 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 36-85) antibodyITGB3BP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-111) antibodyITGB3BP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Li, D., Das, S., Yamada, T., Samuels, H. H. The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells. Molec. Cell. Biol. 24: 3838-3848, 2004. 2. Li, D., Desai-Yajnik, V., Lo, E., Schapira, M., Abagyan, R., Samuels, H. H. NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors. Molec. Cell. Biol. 19: 7191-7202, 1999. 3. Li, D., Wang, F., Samuels, H. H. Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation. Molec. Cell. Biol. 21: 8371-8384, 2001. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
-
别名
- ITGB3BP
-
背景
-
Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
-
分子量
- 20 kDa
-
基因ID
- 23421
-
UniProt
- Q13352
-
途径
- Neurotrophin Signaling Pathway
抗原
-
