ITGB3BP 抗体 (AA 1-177)
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- 抗原 See all ITGB3BP 抗体
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
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抗原表位
- AA 1-177
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITGB3BP antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 原理
- Anti-Centromere protein R/ITGB3BP Antibody Picoband®
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Anti-Centromere protein R/ITGB3BP Antibody Picoband® (ABIN7599037). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Centromere protein R/ITGB3BP recombinant protein (Position: M1-N177). Human ITGB3BP shares 94.4% and 59.8% amino acid (aa) sequence identity with mouse and rat ITGB3BP, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product ITGB3BP Primary Antibody
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anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-100) antibody
ITGB3BP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-177) antibodyITGB3BP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) antibodyITGB3BP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (Internal Region) antibodyITGB3BP 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 36-85) antibodyITGB3BP 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP) (AA 1-111) antibodyITGB3BP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Li, D., Das, S., Yamada, T., Samuels, H. H. The NRIF3 family of transcriptional coregulators induces rapid and profound apoptosis in breast cancer cells. Molec. Cell. Biol. 24: 3838-3848, 2004. 2. Li, D., Desai-Yajnik, V., Lo, E., Schapira, M., Abagyan, R., Samuels, H. H. NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors. Molec. Cell. Biol. 19: 7191-7202, 1999. 3. Li, D., Wang, F., Samuels, H. H. Domain structure of the NRIF3 family of coregulators suggests potential dual roles in transcriptional regulation. Molec. Cell. Biol. 21: 8371-8384, 2001. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))
- 别名
- ITGB3BP (ITGB3BP 产品)
- 背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Centromere protein R is a protein that in humans is encoded by the ITGB3BP gene. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
- 分子量
- 20 kDa
- 基因ID
- 23421
- UniProt
- Q13352
- 途径
- Neurotrophin Signaling Pathway
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