SNAIL 抗体 (AA 1-170)
Quick Overview for SNAIL 抗体 (AA 1-170) (ABIN7599028)
抗原
See all SNAIL (SNAI1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-170
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原理
- Anti-SNAIL/SNAI1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-SNAIL/SNAI1 Antibody Picoband® (ABIN7599028). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SNAIL/SNAI1 recombinant protein (Position: M1-K170).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: SNAI1 snail homolog 1 (Drosophila)". 2. Davidson NE, Sukumar S (September 2005). "Of Snail, mice, and women". Cancer Cell 8(3): 173-4. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SNAIL (SNAI1)
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别名
- SNAI1
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背景
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Synonyms: Emerin,EMD,EDMD, STA,
Tissue Specificity: Skeletal muscle, heart, colon, testis, ovary and pancreas.
Background: The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.
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分子量
- 29 kDa
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基因ID
- 6615
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UniProt
- O95863
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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