HES5 抗体 (AA 1-121)
Quick Overview for HES5 抗体 (AA 1-121) (ABIN7598966)
抗原
See all HES5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-121
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原理
- Anti-HES5 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-HES5 Antibody Picoband® (ABIN7598966). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HES5 recombinant protein (Position: M1-R121).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Katoh, M., Katoh, M. Identification and characterization of human HES2, HES3, and HES5 genes in silico. Int. J. Oncol. 25: 529-534, 2004. 2. Takebayashi, K., Akazawa, C., Nakanishi, S., Kageyama, R. Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5: identification of the neural precursor cell-specific promoter element. J. Biol. Chem. 270: 1342-1349, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HES5 (Hairy and Enhancer of Split 5 (HES5))
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别名
- HES5
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背景
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Synonyms: Cytoskeleton-associated protein 5, Colonic and hepatic tumor overexpressed gene protein, Ch-TOG, CKAP5, KIAA0097
Tissue Specificity: Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala.
Background: Transcription factor HES-5 is a protein that in humans is encoded by the HES5 gene. This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.
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分子量
- 18 kDa
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基因ID
- 388585
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途径
- Stem Cell Maintenance, Tube Formation
抗原
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