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Leptin 抗体 (AA 22-167)

This anti-Leptin antibody is a 小鼠 单克隆 antibody detecting Leptin in WB, ELISA, ICC 和 IF. Suitable for 人.
产品编号 ABIN7596041
发货至: 中国

Quick Overview for Leptin 抗体 (AA 22-167) (ABIN7596041)

抗原

See all Leptin (LEP) 抗体
Leptin (LEP)

适用

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  • 1
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宿主

  • 170
  • 36
  • 7
  • 5
  • 2
  • 1
小鼠

克隆类型

  • 183
  • 37
单克隆

标记

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  • 27
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  • 1
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This Leptin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

克隆位点

AT7E10
  • 抗原表位

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    • 2
    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
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    AA 22-167

    原理

    Human Leptin/OB antibody

    纯化方法

    protein-A affinity chromatography

    免疫原

    Recombinant human Leptin/OB (22-167aa) purified from E. coli.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Leptin (LEP)

    别名

    Leptin/OB

    背景

    Human leptin is a 16- kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarilyin the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated,resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes andinfertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of usingleptin as a therapeutic agent, are currently under intense investigation.

    NCBI登录号

    NP_000221

    途径

    JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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