Leptin 抗体 (AA 22-167)
Quick Overview for Leptin 抗体 (AA 22-167) (ABIN7596041)
抗原
See all Leptin (LEP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 22-167
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原理
- Human Leptin/OB antibody
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纯化方法
- protein-A affinity chromatography
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免疫原
- Recombinant human Leptin/OB (22-167aa) purified from E. coli.
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亚型
- IgG2b kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Leptin (LEP)
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别名
- Leptin/OB
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背景
- Human leptin is a 16- kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarilyin the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated,resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes andinfertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of usingleptin as a therapeutic agent, are currently under intense investigation.
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NCBI登录号
- NP_000221
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途径
- JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
抗原
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