TLR7 抗体 (AA 451-500)
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Quick Overview for TLR7 抗体 (AA 451-500) (ABIN7596035)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 451-500
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原理
- Human TLR7 antibody
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纯化方法
- Purified
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免疫原
- Recombinant human TLR7 (451-500aa) purified from E. coli.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- TLR7 (Toll-Like Receptor 7 (TLR7))
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别名
- TLR7
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背景
- TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity byrecognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine richrepeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptormolecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7, 8 genes are located on the sexchromosome X. hTLR7 may play an important role in detecting and combating viral infections.
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NCBI登录号
- NP_057646
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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