DNMT3L 抗体 (AA 1-387) (FL650)
Quick Overview for DNMT3L 抗体 (AA 1-387) (FL650) (ABIN7595807)
抗原
See all DNMT3L (TRDMT1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-387
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原理
- Anti-DNMT3L Antibody FL650 Conjugate
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特异性
- No off-targets reported for DNMT3A or DNMT3B
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交叉反应
- 人
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产品特性
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Description: Our Anti-DNMT3L mouse monoclonal primary antibody is produced in-house from hybridoma clone N117/9. It detects human DNMT3L, and is purified by Protein A chromatography. It is great for use in ICC.
Manufacturer Comment: We produce our DNMT3L mouse monoclonal primary antibody from hybridoma clone N117/9. It is great in ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 1-387 (full-length) of human DNMT3L (accession number BAA95556) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
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别名
- DNMT3L
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背景
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Synonyms: DNA (cytosine-5)-methyltransferase 3-like
Target Description: DNA (cytosine-5)-methyltransferase 3-like or DNMT3L is encoded by the gene DNMT3L. DNMT3l is a nuclear, catalytically inactive, regulatory factor of DNA methyltransferases. DNMT3L mediates transcriptional repression through interaction with histone deacetylase 1. It is thought to be required for the establishment of maternal genomic imprints. DNMT3L is expressed in several tissues including testis, ovary, and thymus. Diseases associated with DNMT3L include Testicular Spermatocytic Seminoma and Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome.
Gene Name Alternatives: DNMT3L
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分子量
- 45 kDa
抗原
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