Ankyrin G 抗体 (FL550)
Quick Overview for Ankyrin G 抗体 (FL550) (ABIN7595664)
抗原
See all Ankyrin G (ANK3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ankyrin-G (Staining) Antibody FL550 Conjugate
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特异性
- No off-targets reported for Ankyrin-B
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-Ankyrin-G (Staining) mouse monoclonal primary antibody is produced in-house from hybridoma clone N106/65. It detects human, mouse, and rat Ankyrin-G (Staining), and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our Ankyrin-G (Staining) mouse monoclonal primary antibody from hybridoma clone N106/65. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
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别名
- Ankyrin-G
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背景
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Synonyms: Ankyrin-3 (ANK-3) (Ankyrin-G)
Target Description: Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.
Gene Name Alternatives: ANK3
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分子量
- <200 kDa
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途径
- Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development
抗原
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