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Ankyrin G 抗体 (FL550)

This anti-Ankyrin G antibody is a 小鼠 单克隆 antibody detecting Ankyrin G in IHC 和 ICC. Suitable for 人.
产品编号 ABIN7595664
发货至: 中国

Quick Overview for Ankyrin G 抗体 (FL550) (ABIN7595664)

抗原

See all Ankyrin G (ANK3) 抗体
Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Ankyrin G antibody is conjugated to FL550

应用范围

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Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

N106-65
  • 原理

    Anti-Ankyrin-G (Staining) Antibody FL550 Conjugate

    特异性

    No off-targets reported for Ankyrin-B

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Description: Our Anti-Ankyrin-G (Staining) mouse monoclonal primary antibody is produced in-house from hybridoma clone N106/65. It detects human, mouse, and rat Ankyrin-G (Staining), and is purified by Protein A chromatography. It is great for use in IHC, ICC.

    Manufacturer Comment: We produce our Ankyrin-G (Staining) mouse monoclonal primary antibody from hybridoma clone N106/65. It is great in IHC, ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))

    别名

    Ankyrin-G

    背景

    Synonyms: Ankyrin-3 (ANK-3) (Ankyrin-G)

    Target Description: Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.

    Gene Name Alternatives: ANK3

    分子量

    <200 kDa

    途径

    Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development
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