NFASC 抗体 (Intracellular) (FL550)
Quick Overview for NFASC 抗体 (Intracellular) (FL550) (ABIN7595649)
抗原
See all NFASC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Intracellular
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原理
- Anti-Pan-Neurofascin Antibody FL550 Conjugate
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特异性
- No off-targets reported
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交叉反应
- 人, 大鼠
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产品特性
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Description: Our Anti-Pan-Neurofascin mouse monoclonal primary antibody is produced in-house from hybridoma clone L11A/41. It detects human and rat Pan-Neurofascin, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our Pan-Neurofascin mouse monoclonal primary antibody from hybridoma clone L11A/41. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein 1066-1174 (intracellular domain common to NF-155 and NF-186) of rat NF-155 (accession number AAL27854) produced recombinantly in E. Coli
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亚型
- IgG1
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anti-Neurofascin (NFASC) (AA 501-650) antibody
NFASC 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neurofascin (NFASC) (AA 830-1100) antibodyNFASC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurofascin (NFASC) (AA 661-758) antibodyNFASC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neurofascin (NFASC) (C-Term) antibodyNFASC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neurofascin (NFASC) (AA 1142-1155), (Intracellular) antibodyNFASC 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurofascin (NFASC) (AA 760-1007) antibodyNFASC 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- NFASC (Neurofascin (NFASC))
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别名
- Neurofascin
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背景
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Synonyms: Neurofascin NF-155 NF-186
Target Description: Neurofascin is encoded by the gene NFASC. Two major isoforms of NeuroFascin are expressed as a result of alternative splicing, NF186 and NF155. These proteins are expressed in the central nervous system. In brain, NF186 is expressed at Nodes of Ranvier andNF155 is expressed in unmyelinated axons. Neuofascin plays a role in cell adhesion and is thought to be involved in processes such as neurite extension, synaptogenesis and myelination. Diseases associated with this gene include Demyelinating Polyneuropathy.
Gene Name Alternatives: Nfasc
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分子量
- 155, 186 kDa (plus additional bands on immunoblot)
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途径
- Cell-Cell Junction Organization
抗原
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