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Ataxin 1 抗体 (AA 746-761) (FL550)

This anti-Ataxin 1 antibody is a 小鼠 单克隆 antibody detecting Ataxin 1 in ICC. Suitable for 小鼠.
产品编号 ABIN7595598
发货至: 中国

Quick Overview for Ataxin 1 抗体 (AA 746-761) (FL550) (ABIN7595598)

抗原

See all Ataxin 1 (ATXN1) 抗体
Ataxin 1 (ATXN1)

适用

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小鼠

宿主

  • 67
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小鼠

克隆类型

  • 67
  • 52
单克隆

标记

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This Ataxin 1 antibody is conjugated to FL550

应用范围

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Immunocytochemistry (ICC)

克隆位点

N65-37
  • 抗原表位

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    AA 746-761

    原理

    Anti-Ataxin-1, WT Antibody FL550 Conjugate

    特异性

    Minimal off target reactivity for S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot (right)

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Description: Our Anti-Ataxin-1, WT mouse monoclonal primary antibody is produced in-house from hybridoma clone N65/37. It detects human, mouse, and rat Ataxin-1, WT, and is purified by Protein A chromatography. It is great for use in ICC.

    Manufacturer Comment: We produce our Ataxin-1, WT mouse monoclonal primary antibody from hybridoma clone N65/37. It is great in ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Synthetic peptide amino acids 746-761 (RKRRRWSAPETRKLEK) of mouse ataxin-1 (accession number P54254)

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    Ataxin 1 (ATXN1)

    别名

    Ataxin-1

    背景

    Synonyms: Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog)

    Target Description: Ataxin1, also known as spinocerebellar ataxia type 1 protein homolog, is a highly conserved DNA-binding protein. Ataxin1 is expressed in brain and can be found at high levels in the cortex and the hypothalamus in neurons. It is also expressed in other tissues. Within the cell, it is highly expressed in the nucleus, and can also be found in the cytoplasm. Mutations in the ataxin-1 gene cause spinocerebellar ataxia type 1.

    Gene Name Alternatives: Atxn1 Sca1

    分子量

    85 kDa

    途径

    Synaptic Membrane
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